Ipamorelin
A selective pentapeptide ghrelin-receptor agonist prized in research for its clean signaling profile.
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Ipamorelin is a synthetic pentapeptide and one of the most selective growth-hormone-releasing peptides (GHRPs) in research use. It is valued as a research tool for its selectivity relative to earlier GHRPs.
Mechanism & receptor biology
It acts as an agonist at the ghrelin / growth-hormone-secretagogue receptor (GHS-R1a). Research highlights its selectivity — minimal impact on cortisol or prolactin pathways in models — which makes it a clean probe of GHS-R signaling.
Research context
Studied in the GH-axis research context and commonly combined with CJC-1295 to examine GHRH + ghrelin-receptor co-stimulation.
Reference specifications
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH₂ |
|---|---|
| Molecular formula | C₃₈H₄₉N₉O₅ |
| Molecular weight | 711.85 g/mol |
| CAS number | 170851-70-4 |
Ipamorelin is offered strictly for laboratory and research use only. It is not a drug, supplement, or article of food, and is not intended to diagnose, treat, cure, or prevent any disease, nor for human or animal consumption. The information above is an educational summary of published receptor biology and does not constitute medical advice.
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