Melanotan II
A cyclic melanocortin-receptor agonist studied in pigmentation and melanocortin-signaling research.
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Melanotan II is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone. It is a widely studied research probe of the melanocortin-receptor family.
Mechanism & receptor biology
It acts as a non-selective agonist across melanocortin receptors (including MC1R and MC4R). Research examines MC1R-linked pigmentation pathways and MC4R-linked central signaling in model systems.
Research context
Used in melanocortin-pharmacology research as a broad-spectrum reference agonist.
Reference specifications
| Sequence | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ |
|---|---|
| Molecular formula | C₅₀H₆₉N₁₅O₉ |
| Molecular weight | 1024.18 g/mol |
| CAS number | 121062-08-6 |
Melanotan II is offered strictly for laboratory and research use only. It is not a drug, supplement, or article of food, and is not intended to diagnose, treat, cure, or prevent any disease, nor for human or animal consumption. The information above is an educational summary of published receptor biology and does not constitute medical advice.
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