PT-141
A melanocortin-4-receptor-focused peptide studied for central signaling distinct from pigmentation.
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PT-141 (bremelanotide) is a cyclic heptapeptide within the melanocortin family, studied for its relative preference for central melanocortin signaling.
Mechanism & receptor biology
Research focuses on its agonism at the melanocortin-4 receptor (MC4R) in the central nervous system — a pathway distinct from the peripheral pigmentation signaling of MC1R.
Research context
Investigated in melanocortin and central-signaling research as an MC4R-oriented reference peptide.
Reference specifications
| Sequence | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH |
|---|---|
| Molecular formula | C₅₀H₆₈N₁₄O₁₀ |
| Molecular weight | 1025.16 g/mol |
| CAS number | 189691-06-3 |
PT-141 is offered strictly for laboratory and research use only. It is not a drug, supplement, or article of food, and is not intended to diagnose, treat, cure, or prevent any disease, nor for human or animal consumption. The information above is an educational summary of published receptor biology and does not constitute medical advice.
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