GHK-Cu
A naturally occurring copper-binding tripeptide central to skin and matrix-remodeling research.
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GHK-Cu is the tripeptide glycyl-L-histidyl-L-lysine bound to a copper(II) ion. First isolated from human plasma, it is a heavily studied research compound in tissue-remodeling and cosmetic science.
Mechanism & receptor biology
Research explores its high-affinity copper binding and its influence on extracellular-matrix genes, including collagen and metalloproteinase expression, in fibroblast models. The copper complex is considered the biologically relevant research form.
Research context
Used in dermatological, wound-model and matrix-biology research. Appears in cosmetic repair blends (see GLOW, KLOW).
Reference specifications
| Sequence | Gly-His-Lys · Cu²⁺ |
|---|---|
| Molecular formula | C₁₄H₂₄N₆O₄ · Cu |
| Molecular weight | ≈403.9 g/mol (complex) |
| CAS number | 49557-75-7 |
GHK-Cu is offered strictly for laboratory and research use only. It is not a drug, supplement, or article of food, and is not intended to diagnose, treat, cure, or prevent any disease, nor for human or animal consumption. The information above is an educational summary of published receptor biology and does not constitute medical advice.
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