TB-500
A synthetic peptide based on the actin-binding region of Thymosin β4, studied in tissue-repair models.
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TB-500 is a synthetic peptide corresponding to the biologically active, actin-binding region of Thymosin β4, a naturally occurring regulatory protein. It is investigated alongside BPC-157 as a core tissue-repair research compound.
Mechanism & receptor biology
Research focuses on its interaction with G-actin and the promotion of cell migration and angiogenesis in model systems. The parent protein, Thymosin β4, is a well-characterized actin-sequestering peptide, and TB-500 is studied as its accessible research fragment.
Research context
Used in laboratory studies of cell motility, vascular formation and connective-tissue biology. Frequently combined with BPC-157 in blends (see Wolverine, GLOW, KLOW).
Reference specifications
| Sequence | Thymosin β4 active fragment (e.g., Ac-LKKTETQ) |
|---|---|
| Molecular formula | Fragment of Tβ4 (C₂₁₂H₃₅₀N₅₆O₇₈S) |
| Molecular weight | varies by fragment |
| CAS number | 77591-33-4 (Tβ4) |
TB-500 is offered strictly for laboratory and research use only. It is not a drug, supplement, or article of food, and is not intended to diagnose, treat, cure, or prevent any disease, nor for human or animal consumption. The information above is an educational summary of published receptor biology and does not constitute medical advice.
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