SS-31
A mitochondria-targeting tetrapeptide studied for its association with cardiolipin and cristae stability.
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SS-31 (also known as elamipretide) is a cell-permeable, mitochondria-targeting tetrapeptide that concentrates on the inner mitochondrial membrane. It is one of the most-studied compounds in mitochondrial-bioenergetics research.
Mechanism & receptor biology
Research investigates its selective binding to cardiolipin on the inner mitochondrial membrane and the reported effects on cristae architecture, electron-transport efficiency and reactive-oxygen-species handling in model systems.
Research context
Used in mitochondrial-function, bioenergetics and cellular-aging research as a reference membrane-targeting peptide.
Reference specifications
| Sequence | D-Arg-Dmt-Lys-Phe-NH₂ |
|---|---|
| Molecular formula | C₃₂H₄₉N₉O₅ |
| Molecular weight | 639.79 g/mol |
| CAS number | 736992-21-5 |
SS-31 is offered strictly for laboratory and research use only. It is not a drug, supplement, or article of food, and is not intended to diagnose, treat, cure, or prevent any disease, nor for human or animal consumption. The information above is an educational summary of published receptor biology and does not constitute medical advice.
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